DNP-PEG4-NHS ester

Description: DNP-PEG4-NHS ester, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: O=C(ON1C(=O)CCC1=O)CCOCCOCCOC COCCNC2=CC=C(C=C2N(=O)=O)N(=O)=O. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct,36:553-562