DMABA NHS ester

Phosphatidylethanolamine (PE) lipids are important components of cell membranes and biochemical pathways of fatty acid synthesis that contain abundant polyunsaturated fatty acyl (PUFA) groups. Oxidation of these phospholipids may be linked to various human diseases. DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. This facilitates the use of electrospray tandem mass spectrometry for the detection of diacyl, ether, and plasmalogen PE lipids that cannot be readily observed otherwise. DMABA NHS ester has been used in combination with DMABA NHS ester-d4, -d6, and -d10 (Cay-11217, 11218, and 11219) to study relative changes in PE lipid abundance before and after radical oxidation.Formal Name: 4-(dimethylamino)-benzoic acid, 2,5-dioxo-1-pyrrolidinyl ester. CAS Number: 58068-85-2. Synonyms: 4-(dimethylamino) Benzoic Acid, DMABA N-hydroxysuccinimide ester, N-Succinimidyl 4-(dimethylamino)benzoate. Molecular Formula: C13H14N2O4. Formula Weight: 262.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:30): 0.03 mg/ml, Ethanol: Insoluable, PBS (pH 7.2): Insoluable. lambdamax: 235,323 nm. SMILES: O=C(CC1)N(OC(C2=CC=C(N(C)C)C=C2)=O)C1=O. InChi Code: InChI=1S/C13H14N2O4/c1-14(2)10-5-3-9(4-6-10)13(18)19-15-11(16)7-8-12(15)17/h3-6H,7-8H2,1-2H3. InChi Key: FNGFZOAQGYOQTG-UHFFFAOYSA-N.