DL-Propargyl Glycine (hydrochloride)

DL-Propargyl Glycine (hydrochloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010948-1 1 mg -

6 - 10 business days*

15.00€
Cay10010948-5 5 mg -

6 - 10 business days*

68.00€
Cay10010948-10 10 mg -

6 - 10 business days*

120.00€
Cay10010948-50 50 mg -

6 - 10 business days*

525.00€
 
Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and... more
Product information "DL-Propargyl Glycine (hydrochloride)"
Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and pro-inflammatory mediator. DL-Propargyl glycine (PAG) is an irreversible inhibitor of the H2S synthesizing enzyme cystathionine-gamma-lyase (CSE). PAG blocks H2S synthesis activity in rat liver preparations with an IC50 value of 55 µM and abolishes the rise in plasma H2S in anaesthetized rats induced with hemorrhagic shock. At concentrations ranging from 25-100 mg/kg, PAG can reduce H2S-associated inflammation in rodent models of pancreatitis, oedema, and endotoxemia. Formal Name: 2-amino-4-pentynoic acid, monohydrochloride. CAS Number: 16900-57-5. Synonyms: PAG. Molecular Formula: C5H7NO2 . HCl. Formula Weight: 149.6. Purity: >95%. Formulation: A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: NC(C(O)=O)CC#C.Cl. InChi Code: InChI=1S/C5H7NO2.ClH/c1-2-3-4(6)5(7)8,/h1,4H,3,6H2,(H,7,8),1H. InChi Key: UAMBUICGODABQY-UHFFFAOYSA-N.
Keywords: PAG, 2-amino-4-pentynoic acid, monohydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 10010948

Properties

Application: CSE inhibitor
MW: 149.6 D
Formula: C5H7NO2 . HCl
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 16900-57-5| Find alternatives
KEGG ID : K01758 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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