DL-Folinic Acid (calcium salt)

DL-Folinic acid is a formylated form of tetrahydrofolic acid (Cay-18263), the reduced form of folic acid, a B vitamin. DL-Folinic acid is used to prevent toxicity following therapy with high-dose methotrexate (Cay-13960), to enhance the antitumor activity of 5-fluorouracil (Cay-14416), and as a folate supplement.Formal Name: N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, monocalcium salt. CAS Number: 1492-18-8. Synonyms: DL-Folinate, NSC 3590, 5-Formyltetrahydrofolate. Molecular Formula: C20H21N7O7 . Ca. Formula Weight: 511.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: 0.3 mg/ml. lambdamax: 220, 287 nm. SMILES: O=CN1C(CNC2=CC=C(C(N[C@H](C([O-])=O)CCC([O-])=O)=O)C=C2)CNC3=C1C(N=C(N)N3)=O.[Ca+2]. InChi Code: InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30,/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32),/q,+2/p-2/t12?,13-,/m0./s1. InChi Key: KVUAALJSMIVURS-ZEDZUCNESA-L.