Diquat (bromide)

Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS). Diquat administration has been used to induce oxidative stress in vitro and in animal models. It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg. Formulations containing diquat have been used in agriculture for crop desiccation and defoliation.Formal Name: 6,7-dihydro-dipyrido[1,2-a:2',1'-c]pyrazinediium, dibromide. CAS Number: 85-00-7. Molecular Formula: C12H12N2 . 2Br. Formula Weight: 344.0. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, Ethanol: slightly soluble. lambdamax: 312 nm. SMILES: [N+]12=CC=CC=C1C3=[N+](C=CC=C3)CC2.[Br-].[Br-]. InChi Code: InChI=1S/C12H12N2.2BrH/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1,,/h1-8H,9-10H2,2*1H/q+2,,/p-2. InChi Key: ODPOAESBSUKMHD-UHFFFAOYSA-L.