Diphenyleneiodonium (chloride)

Diphenyleneiodonium (chloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay81050-5 5 mg -

6 - 10 business days*

60.00€
Cay81050-10 10 mg -

6 - 10 business days*

94.00€
 
Diphenyleneiodonium (DPI) is an inhibitor of NADPH oxidase (NOX, EC50 = 0.1 µM in HeLa cells). It... more
Product information "Diphenyleneiodonium (chloride)"
Diphenyleneiodonium (DPI) is an inhibitor of NADPH oxidase (NOX, EC50 = 0.1 µM in HeLa cells). It also inhibits nitric oxide synthase (NOS, IC50 = 0.05 µM in isolated mouse peritoneal macrophages). DPI (10, 50, and 100 µM) induces the production of reactive oxygen species (ROS) in, and apoptosis of, human umbilical vein endothelial cells (HUVECs). It inhibits NETosis induced by phorbol 12-myristate 13-acetate (PMA, Cay-10008014) in isolated human neutrophils when used at a concentration of 10 µM. DPI (2 mg/kg) reduces tumor growth in HT-29 and LS 174T colon cancer mouse xenograft models.Formal Name: dibenziodolium chloride. CAS Number: 4673-26-1. Synonyms: DPI. Molecular Formula: C12H8I . Cl. Formula Weight: 314.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 500 µg/ml, Ethanol: <100 µg/ml, Methanol: <100 µg/ml. SMILES: C12=C(C3=C([I+]2)C=CC=C3)C=CC=C1.[Cl-]. InChi Code: InChI=1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11,/h1-8H,1H/q+1,/p-1. InChi Key: FCFZKAVCDNTYID-UHFFFAOYSA-M.
Keywords: DPI, dibenziodolium chloride
Supplier: Cayman Chemical
Supplier-Nr: 81050

Properties

Application: iNOS inhibitor, eNOS inhibitor
MW: 314.5 D
Formula: C12H8I . Cl
Purity: >99%
Format: Crystalline Solid

Database Information

CAS : 4673-26-1| Matching products
KEGG ID : K13242 | Matching products

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H319
P Phrases: P264, P280, P305+P351+P338, P337+P313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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