Dinaciclib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Dinaciclib (SCH 727965) is a selective CDK inhibitor targeting CDK1, CDK2, CDK5, and... more
Product information "Dinaciclib"
Description: Dinaciclib (SCH 727965) is a selective CDK inhibitor targeting CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM). It exhibits potential antitumor activity by inhibiting the incorporation of thoracic glycan (dThd) DNA. Target: CDK, Apoptosis. Smiles: N(CC1=CN(=O)=CC=C1)C=2N3C(N=C(C2)N4[C@H](CCO)CCCC4)=C(CC)C=N3. References: Feldmann G, et al. Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models. Cancer Biol Ther. 2011 Oct 1,12(7):598-609.
| Keywords: | PS-095760, SCH 727965 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1912 |
Properties
| Application: | Targets cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23] (CDK1, CDC2) |
| MW: | 396.49 D |
| Formula: | C21H28N6O2 |
Database Information
| CAS : | 779353-01-4| Matching products |
| KEGG ID : | K02087 | Matching products |
| Protein Atlas Nr. : | Apoptosis, Cell Cycle, DNA Repair |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H340, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P321, P302+P352, P305+P351+P338, P308+P313, P332+P313, P337+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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