Demethoxycurcumin

Demethoxycurcumin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CDX-D0929-M005 5 mg - -

3 - 9 business days*

99.00€
CDX-D0929-M025 25 mg - -

3 - 9 business days*

337.00€
 
Yellow to orange powder. Soluble in DMSO (10mg/ml) or DMF (10mg/ml). Chemical. CAS: 22608-11-3.... more
Product information "Demethoxycurcumin"
Yellow to orange powder. Soluble in DMSO (10mg/ml) or DMF (10mg/ml). Chemical. CAS: 22608-11-3. Formula: C20H18O5. MW: 338.35. Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin with anti-inflammatory and anti-cancer properties. DMC suppresses cell proliferation, migration and invasion in cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/beta-catenin pathway, and inhibits lipopolysaccharide induction of iNOS by blocking NF-kappa activation. It also has been shown to inhibit energy metabolic and oncogenic signaling pathways through AMPK activation. In addition it is a potent inhibitor of P-Type ATPases. Shown to have neuroprotective properties. It also has anti-plasmodial activity.
Keywords: DMC, (E,E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, Desmethoxycurcumin, Monodemethoxycurcumin
Supplier: Chemodex
Supplier-Nr: D0929

Properties

Host: Plant
MW: 338,35 D
Formula: C20H18O5
Purity: > 98% (HPLC)
Format: Solid

Database Information

CAS : 22608-11-3| Matching products

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H400
P Phrases: P273
Caution
Our products are for laboratory research use only: Not for administration to humans!
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