(+)-delta-Cadinene

Description: (+)-delta-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 µg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 and 3 against third instar larvae of A. stephensi, A. aegypti and C. quinquefasciatust, respectively.(+)-delta-Cadinene (10, 50 and 100 µM) induced apoptosis and inhibited the growth of OVCAR-3 human ovarian cancer cells apoptosis and inhibited their proliferation. Target: Antibacterial, Apoptosis. Smiles: [C@@H](C)(C)[C@H]1[C@]2(C(=C(C)CC1)CCC(C)=C2)[H]. References: Meng YL, et al. Coordinated accumulation of (+)-delta-cadinene synthase mRNAs and gossypol in developing seeds of Gossypium hirsutum and a new member of the cad1 family from G. arboreum. J Nat Prod. 1999,62(2):248-252.