Decatromicin B

Decatromicin B is a bacterial metabolite that has been found in Actinomadura. It is active against Gram-positive bacteria, including several strains of S. aureus (MICs = 0.39-0.78 µg/ml), two strains of methicillin-resistant S. aureus (MRSA, MICs = 0.39 and 0.78 µg/ml), as well as M. luteus, B. subtilis, and C. bovis (MICs = 0.78, 0.78, and 6.25 µg/ml, respectively).Formal Name: (3S,4S,4aS,6aR,8E,11E,12aS,15S,16aS,20aR,20bR)-15,20a-diethyl-1,2,3,4,4a,6a,7,10,12a,15,16,20,20a,20b-tetradecahydro-21-hydroxy-3,11,12a-trimethyl-18,20-dioxo-4-[[2,4,6-trideoxy-4-[[(3,5-dichloro-1H-pyrrol-2-yl)carbonyl]amino]-beta-D-arabino-hexopyranosyl]oxy]-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-14-carboxylic acid. CAS Number: 235097-64-0. Molecular Formula: C45H56Cl2N2O10. Formula Weight: 855.8. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: CC[C@@H]1C(C(O)=O)=C[C@@](/C=C(C)\C/C=C/C[C@@](C=C[C@@]2([H])[C@@]3([H])CC[C@H](C)[C@@H]2O[C@]4([H])O[C@H](C)[C@@H](NC(C5=C(Cl)C=C(Cl)N5)=O)[C@H](O)C4)([H])[C@@]3(CC)C(C6=C7O)=O)(C)[C@@]7(OC6=O)C1. InChi Code: InChI=1S/C45H56Cl2N2O10/c1-7-25-20-45-39(52)34(42(56)59-45)38(51)44(8-2)26(12-10-9-11-22(3)19-43(45,6)21-28(25)41(54)55)14-15-27-29(44)16-13-23(4)37(27)58-33-18-31(50)35(24(5)57-33)49-40(53)36-30(46)17-32(47)48-36/h9-10,14-15,17,19,21,23-27,29,31,33,35,37,48,50,52H,7-8,11-13,16,18,20H2,1-6H3,(H,49,53)(H,54,55)/b10-9+,22-19-/t23-,24+,25-,26+,27-,29+,31+,33-,35+,37-,43-,44+,45+/m0/s1. InChi Key: OKYWSSBYCHUWKT-FSDPHVPFSA-N. Origin: Bacterium/Streptomyces sp..