Darizmetinib

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T72956-25mg	25 mg				7 - 10 business days*		1,222.00€
TGM-T72956-50mg	50 mg				7 - 10 business days*		1,877.00€

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Description: Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to... more

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Product information "Darizmetinib"

Description: Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration. Target: Antiviral, MAPK. Smiles: O=C(C1=NNC2=NC=C(C=C21)C=3C=CN=CC3)C4=CC=C(F)C(NS(=O)(=O)CCC)=C4F. References: Praefke B, et al. Preparation of pyrazolopyridines as protein kinase MKK4 inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death: World Intellectual Property Organization, WO2019149738. 2019-08-08.

Keywords:	HRX215, HRX-0215
Supplier:	TargetMol
Supplier-Nr:	T72956

Properties

MW:	457.45 D
Formula:	C21H17F2N5O3S

Database Information

CAS :

2369583-33-3| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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