Cytochalasin C

Cytochalasin C is an actin polymerization inhibitor and fungal metabolite that has been found in C. globosum. It inhibits actin polymerization when used at a concentration of 10 µM. Cytochalasin C is cytotoxic to HeLa cells (IC50 = <0.32 µg/ml).Formal Name: (3S,3aR,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione. CAS Number: 22144-76-9. Molecular Formula: C30H37NO6. Formula Weight: 507.6. Purity: >99%. Formulation: (Request formulation change), A powder. Solubility: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble. SMILES: O[C@H]1[C@H]2[C@@]3([C@@H](/C=C/[C@@](C)(O)C([C@@H](C)C/C=C/2)=O)OC(C)=O)C([C@H](CC4=CC=CC=C4)NC3=O)C(C)=C1C. InChi Code: InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17,22-26,33,36H,10,16H2,1-5H3,(H,31,35)/b13-9+,15-14+/t17-,22-,23-,24?,25?,26+,29+,30+/m0/s1. InChi Key: NAIODHJWOHMDJX-GHFBPWLISA-N. Origin: Fungus/Geniculosporium sp..