Cytidine 5'-triphosphate (sodium salt hydrate)

Cytidine 5'-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.Formal Name: cytidine 5'-(tetrahydrogen triphosphate), disodium salt, hydrate. CAS Number: 652154-13-7. Synonyms: CTP, NSC 20261. Molecular Formula: C9H14N3O14P3 . 2Na [XH2O]. Formula Weight: 527.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 275 nm. SMILES: O=P(OP(OP(O)([O-])=O)(O)=O)([O-])OC[C@H]1O[C@@H](N2C(N=C(N)C=C2)=O)[C@H](O)[C@@H]1O.[Na+].[Na+].O. InChi Code: InChI=1S/C9H16N3O14P3.2Na.H2O/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18,,,/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18),,,1H2/q,2*+1,/p-2/t4-,6-,7-,8-,,,/m1.../s1. InChi Key: IJMSOWKYYIROGP-LLWADOMFSA-L.