Cysteamine-d4 (hydrochloride)

Cysteamine-d4 is intended for use as an internal standard for the quantification of cysteamine (hydrochloride) (Cay-22193) by GC- or LC-MS. Cysteamine is a stable aminothiol with radioprotective activities. It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner. Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects. In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts. Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.Formal Name: 2-amino-ethanethiol-d4, monohydrochloride. CAS Number: 1219805-04-5. Synonyms: beta-Mercaptoethylamine-d4. Molecular Formula: C2H3D4NS . HCl. Formula Weight: 117.6. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble. SMILES: NC([2H])([2H])C([2H])([2H])S.Cl. InChi Code: InChI=1S/C2H7NS.ClH/c3-1-2-4,/h4H,1-3H2,1H/i1D2,2D2,. InChi Key: OGMADIBCHLQMIP-PBCJVBLFSA-N.