Cyclocreatine

Cyclocreatine is a planar creatine analog that can passively transit across membranes, including the blood brain barrier, and is phosphorylated and dephosphoryated by mitochondrial and cytosolic creatine kinase. Cyclocreatine can function as a phosphagen in mouse brain in vivo and has been used to reverse cognitive deficits in Slc6a8-/y mice that lack a functional creatine transporter.Formal Name: 2-amino-4,5-dihydro-1H-imidazole-1-acetic acid. CAS Number: 35404-50-3. Synonyms: AM 285, 1-Carboxymethyl-2-iminoimidazolidine. Molecular Formula: C5H9N3O2. Formula Weight: 143.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 2 mg/mL. SMILES: NC1=NCCN1CC(O)=O. InChi Code: InChI=1S/C5H9N3O2/c6-5-7-1-2-8(5)3-4(9)10/h1-3H2,(H2,6,7)(H,9,10). InChi Key: AMHZIUVRYRVYBA-UHFFFAOYSA-N.