Curcumenol

Curcumenol is a sesquiterpene that has been found in Curcuma species. It is active against methicillin-resistant S. aureus (MRSA) and P. aeruginosa and cytotoxic to CEM-SS lymphoblastic leukemia cells (IC50 = 11.9 µg/ml). It also decreases cell viability of AGS human gastric carcinoma cells (IC50 = 263.34 µM).Formal Name: (3S,3aS,6R,8aS)-1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-6H-3a,6-epoxyazulen-6-ol. CAS Number: 19431-84-6. Synonyms: (+)-Curcumenol. Molecular Formula: C15H22O2. Formula Weight: 234.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 5 mg/ml, Ethanol: 3 mg/ml, PBS (pH 7.2): 0.3 mg/ml. lambdamax: 262 nm. SMILES: CC([C@@]1([H])[C@]([C@@H](C)CC1)(O2)C/3)=C[C@]2(O)C3=C(C)/C. InChi Code: InChI=1S/C15H22O2/c1-9(2)13-8-14-11(4)5-6-12(14)10(3)7-15(13,16)17-14/h7,11-12,16H,5-6,8H2,1-4H3/t11-,12-,14-,15+/m0/s1. InChi Key: ISFMXVMWEWLJGJ-NZBPQXDJSA-N. Origin: Plant/Curcumae Rhizoma.