CTPI-2
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 µM).... more
Product information "CTPI-2"
Description: CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 µM). CTPI-2 inhibits glycolysis, PPARgamma, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Target: Mitochondrial Metabolism, Others. Smiles: OC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O. References: Tan M, et al. Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. Cell Death Differ. 2020,27(7):2143-2157.
| Supplier: | TargetMol |
| Supplier-Nr: | T8732 |
Properties
| Application: | Mitochondrial citrate transporter inhibitor |
| MW: | 356.74 D |
| Formula: | C13H9ClN2O6S |
Database Information
| CAS : | 68003-38-3| Matching products |
| KEGG ID : | K15100 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H312, H315, H319, H332, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P361+P364, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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