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Description: CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on neurokinin-related respiratory diseases. Target: Neurokinin receptor. Smiles: O=S1C2(C=3C(C1)=CC=CC3)CCN(CC[C@]4(CN(C(=O)C5=CC(OC)=C(OC)C(OC)=C5)CCO4)C6=CC(Cl)=C(Cl)C=C6)CC2. References: Tsuchida H, et al. Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses. Eur J Pharmacol. 2008 May 31,586(1-3):306-12.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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