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Crovalimab

TargetMol
Crovalimab
NEW
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T77190-1mg 1 mg - - -

7 - 10 business days*

233.00€
TGM-T77190-10mg 10 mg - - -

7 - 10 business days*

934.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Description: Crovalimab (SKY59, RO7112689) is an Fc-engineered and pH-dependent humanised... more
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Product information "Crovalimab"
Description: Crovalimab (SKY59, RO7112689) is an Fc-engineered and pH-dependent humanised monoclonal antibody that binds to complement C5 and blocks its cleavage into C5a and C5b, thereby inhibiting MAC formation and intravascular haemolysis. It can rebind to the FcRn receptor under acidic pH conditions and return to the bloodstream, making it suitable for the treatment of paroxysmal nocturnal haemoglobinuria (PNH). Target: Complement System. References: Taku Fukuzawa, et al. Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases. Sci Rep. 2017 Apr 24,7(1):1080.
Keywords: SKY59 , SKY 59 , RO7112689 , RO 7112689
Supplier: TargetMol
Supplier-Nr: T77190

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Our products are for laboratory research use only: Not for administration to humans!
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