Coumarin Boronic Acid

Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite (Cay-81565), hypochlorous acid, and hydrogen peroxide.It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 µM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.Formal Name: B-(2-oxo-2H-1-benzopyran-7-yl)-boronic acid. CAS Number: 1357078-03-5. Synonyms: CBA. Molecular Formula: C9H7BO4. Formula Weight: 190.0. Purity: >98%. Emission: 470 nm. Excitation: 332 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 11 mg/ml, DMSO: 3 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 1 mg/ml. lambdamax: 280, 320 nm. SMILES: O=C1OC2=CC(B(O)O)=CC=C2C=C1. InChi Code: InChI=1S/C9H7BO4/c11-9-4-2-6-1-3-7(10(12)13)5-8(6)14-9/h1-5,12-13H. InChi Key: MUZVCJQIBNTECF-UHFFFAOYSA-N.