Coenzyme A (lithium salt hydrate)

Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid (Cay-17288) in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway has been identified as a target for the development of antibacterial compounds.Synonyms: CoA. Molecular Formula: C21H33N7O16P3S . XLi [XH2O]. Formula Weight: 764.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 260 nm. SMILES: O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.O.[Li]. InChi Code: InChI=1S/C21H36N7O16P3S.Li.H2O/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28,,/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35),,1H2/t11-,14-,15-,16+,20-,,/m1../s1. InChi Key: LQHTWTXOGIRXQR-CLVRNSBASA-N.