Coblopasvir (hydrochloride)

Coblopasvir is a pan-genotypic inhibitor of hepatitis C virus (HCV) non-structural protein 5A (NS5A). It inhibits viral replication of the HCV genotypes 1a, -1b, -3a, -4a, -5a, and -6a in cellular assays and genotype 2a in a cell-free assay.Formal Name: N-[(1S)-1-[[(2S)-2-[5-[4-[7-[2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1H-imidazol-5-yl]-1,3-benzodioxol-4-yl]phenyl]-1H-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-carbamic acid, methyl ester, dihydrochloride. CAS Number: 1966138-53-3. Molecular Formula: C41H50N8O8 . 2HCl. Formula Weight: 855.8. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Water: Soluble. SMILES: O=C([C@H](C(C)C)NC(OC)=O)N1CCC[C@@]1([H])C2=NC=C(C3=CC=C(C4=CC=C(C5=CN=C([C@]6([H])CCCN6C([C@@H](NC(OC)=O)C(C)C)=O)N5)C7=C4OCO7)C=C3)N2.Cl.Cl. InChi Code: InChI=1S/C41H50N8O8.2ClH/c1-22(2)32(46-40(52)54-5)38(50)48-17-7-9-30(48)36-42-19-28(44-36)25-13-11-24(12-14-25)26-15-16-27(35-34(26)56-21-57-35)29-20-43-37(45-29)31-10-8-18-49(31)39(51)33(23(3)4)47-41(53)55-6,,/h11-16,19-20,22-23,30-33H,7-10,17-18,21H2,1-6H3,(H,42,44)(H,43,45)(H,46,52)(H,47,53),2*1H/t30-,31-,32-,33-,,/m0../s1. InChi Key: NQXPKJCTLPFQIS-KJIUXTSNSA-N.