Cnidilin

Source/Host Chemicals: Plant. Purity Chemicals: >98% (HPLC) Appearance: Light yellow powder. Solubility: Soluble in DMSO (3mg/ml) or chloroform. Identity: Determined by 1H-NMR. InChi Key: NNDOCYLWULORAM-UHFFFAOYSA-N Smiles: O=C(C=C1)OC2=C1C(OC/C=C(C)/C)=C(C=CO3)C3=C2OC Cnidilin is a natural compound belonging to the coumarin family and normally isolated from Radix Angelicae dahuricae (RAD), a traditional Chinese medicine (TCM). RAD possesses anti-oxidant, anti-cancer and anti-inflammatory effects. Cnidilin has been described to show strong antiplatelet aggregation activity in vitro to be a GABAA receptor ligand and NO production inhibitor. Product References: [1] I.S. Chen, et al., Phytochemistry 41, 525 (1996) , [2] C.C. Wang, et al., Bioorg. Med. Chem. 8, 2701 (2000) , [3] Z. Janine, et al., Fitoterapia 82, 434 (2011) , [4] Y. Huang, et al., ACS Omega 7, 27369 (2022)