Clothianidin-d3

Clothianidin-d3 is deuterium labelled Clothianidin, which is a neonicotinoid insecticide. Neonicotinoids (NNIs) are a family of active substances used in plant protection to control harmful insects and also in veterinary medicine. Neonicotinoids act selectively on the insect nicotinic acetylcholine receptors (nAChRs), initially stimulating postsynaptic receptors, increasing Na+ ingress and K+ egress and then paralyzing nerve conduction, resulting in rapid death. This compound can be used as a reference compound, in the determination of several neonicotinoid insecticides present in bee pollen, using ultra-high performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS). Product References: (1) M.Chen, et al., J. Agric. Food Chem. 62, 6082 (2014) , (2) A. Schaafsma, et al., PLOSone 10, e0118139 (2015) , (3) Y.-F. Huang, et al., Appl. Sci. 10, 6775 (2020) Appearance: White to light brown powder. Solubility: Soluble in chloroform, acetone or acetonitrile. Identity: Determined by 1H-NMR. InChi Key: PGOOBECODWQEAB-FIBGUPNXSA-N Smiles: ClC1=NC=C(CN/C(NC([2H])([2H])[2H])=N/[N+]([O-])=O)S1