CL2-SN-38

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T10832-50mg	50 mg				7 - 10 business days*		785.00€
TGM-T10832-100mg	100 mg				7 - 10 business days*		1,412.00€

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Description: CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the... more

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Product information "CL2-SN-38"

Description: CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is an inhibitor of DNA topoisomerase I. Target: Others, Drug-Linker Conjugates for ADC. Smiles: CCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)OCc4ccc(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc5ccccc5)NC(=O)COCC(=O)NCCOCCOCCO CCOCCOCCOC COCCOCCn5cc(CNC(=O)C6CCC(CN7C(=O)C=CC7=O)CC6)nn5)cc4)c3=O)-c2nc2ccc(O)cc12. References: Cardillo TM, et al. Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. Clin Cancer Res. 2011 May 15,17(10):3157-69.

Supplier:	TargetMol
Supplier-Nr:	T10832

Properties

MW:	1627.79 D
Formula:	C82H106N12O23

Database Information

CAS :

1036969-20-6| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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