cis-Lomibuvir

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T73814-10mg	10 mg				7 - 10 business days*		788.00€
TGM-T73814-25mg	25 mg				7 - 10 business days*		1,754.00€

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Description: Cis-Lomibuvir (cis-VX-222), a cis-isomer of Lomibuvir, is a selective non-nucleoside... more

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Product information "cis-Lomibuvir"

Description: Cis-Lomibuvir (cis-VX-222), a cis-isomer of Lomibuvir, is a selective non-nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase (RdRp), targeting thumb pocket 2 with a dissociation constant (Kd) of 17 nM. It exhibits an EC50 of 5.2 nM against the 1b/Con1 HCV subgenomic replicon, demonstrating a preference for inhibiting elongative RNA synthesis over de novo-initiated RNA synthesis. Target: Others. Smiles: C[C@H]1CC[C@@H](CC1)C(=O)N([C@@H]1CC[C@@H](CC1)O)c1c(sc(c1)C#CC(C)(C)C)C(=O)O

Supplier:	TargetMol
Supplier-Nr:	T73814

Properties

Application:	Antiviral, NS5B polymerase inhibitor
MW:	445.61 D
Formula:	C25H35NO4S

Database Information

CAS :	1026785-59-0\| Matching products
KEGG ID :	K22472 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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