CID44216842
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Description: CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding... more
Product information "CID44216842"
Description: CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 µM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 µM in GDP binding assay, respectively. Use as a molecular probe. Target: CDK, Ras. Smiles: COc1cccc(c1)C1=NN(C(C1)c1ccc(Br)cc1)c1ccc(cc1)S(N)(=O)=O. References: Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22,288(12):8531-43.
| Keywords: | KUC103479N-02 |
| Supplier: | TargetMol |
| Supplier-Nr: | T8930 |
Properties
| Application: | Cdc42 inhibitor |
| MW: | 486.38 D |
| Formula: | C22H20BrN3O3S |
Database Information
| CAS : | 1222513-26-9| Matching products |
| KEGG ID : | K04393 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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