CHIR-99021
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: CHIR-99021 (CT99021) is an activator of the Wnt/beta-catenin signaling pathway and a... more
Product information "CHIR-99021"
Description: CHIR-99021 (CT99021) is an activator of the Wnt/beta-catenin signaling pathway and a GSK-3alpha/beta inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells. Target: Autophagy, GSK-3, Wnt/beta-catenin. Smiles: Cl.Cc1c[nH]c(n1)-c1cnc(NCCNc2ccc(cn2)C#N)nc1-c1ccc(Cl)cc1Cl. References: Naujok O, et al. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors. BMC Res Notes. 2014 Apr 29,7:273.
| Keywords: | Laduviglusib, CHIR-99021, CT99021 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2310 |
Properties
| MW: | 465.34 D |
| Formula: | C22H18Cl2N8 |
Database Information
| CAS : | 252917-06-9| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H300, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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