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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay22175-1 | 1 mg | - |
6 - 10 business days* |
84.00€
|
|||
Cay22175-5 | 5 mg | - |
6 - 10 business days* |
320.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cercosporin is a pigmented phytotoxin isolated from the fungus C. kikuchii that produces reactive... more
Product information "Cercosporin"
Cercosporin is a pigmented phytotoxin isolated from the fungus C. kikuchii that produces reactive oxygen species in plant hosts leading to cellular damage. It exhibits light-activated cytotoxic effects in vitro with cytotoxic concentration (CC50) values of 241, 282, and 174 nM in HeLa, A432, and MCF-7 cells, respectively. It is a selective inhibitor of PKC (IC50 = 600-1,300 nM) with no activity on PKA or PPK at concentrations over 180 µM.Formal Name: (13bR)-6,12-dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-5,11-dione. CAS Number: 35082-49-6. Synonyms: CGP 049090, NSC 153111. Molecular Formula: C29H26O10. Formula Weight: 534.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble. lambdamax: 225, 269, 470 nm. SMILES: COC(C1=O)=C(CC(O)C)C2=C3C(C(C(C=C4OCO5)=O)=C(O)C(OC)=C3CC(C)O)=C4C6=C5C=C(O)C1=C26. InChi Code: InChI=1S/C29H26O10/c1-10(30)5-12-18-19-13(6-11(2)31)29(37-4)27(35)21-15(33)8-17-23(25(19)21)22-16(38-9-39-17)7-14(32)20(24(18)22)26(34)28(12)36-3/h7-8,10-11,30-32,35H,5-6,9H2,1-4H3. InChi Key: JWFLIMIGORGZMQ-UHFFFAOYSA-N. Origin: Fungus/Cercospora sp..
Keywords: | CGP 049090, NSC 153111, (13bR)-6,12-dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-5,11-dione |
Supplier: | Cayman Chemical |
Supplier-Nr: | 22175 |
Properties
Application: | Lighted-activated cytotoxic agent |
MW: | 534.5 D |
Formula: | C29H26O10 |
Purity: | >95% |
Format: | Solid |
Database Information
CAS : | 35082-49-6| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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