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Description: Ceapin-A7, with an IC50 of 0.59 µM, selectively inhibits ATF6alpha signaling in response to ER stress. This compound is instrumental in investigating ATF6alpha's activation mechanism and its function in pathological conditions. Target: Others. Smiles: FC(F)(F)c1ccc(Cn2cc(NC(=O)c3cc(on3)-c3ccco3)cn2)c(c1)C(F)(F)F. References: Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6alpha branch. eLife. 2016, 5: e11878.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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