CDK9-Cyclin T1 PPI-IN-1

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T82758-5mg	5 mg				5 - 10 business days*		-
TGM-T82758-50mg	50 mg				5 - 10 business days*		-

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Description: CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin... more

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Product information "CDK9-Cyclin T1 PPI-IN-1"

Description: CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 µM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1]. Target: CDK

Supplier:	TargetMol
Supplier-Nr:	T82758

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Storage:	-20°C
Shipping:	+20°C (International: +4°C)

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Our products are for laboratory research use only: Not for administration to humans!

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