CCK Octapeptide (sulfated) (ammonium salt)

Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. It is a cleaved product of the full CCK preprohormone that is more potent than the full-length enzyme in stimulating contraction of guinea pig gallbladder but with a shorter duration.1,3 CCK octapeptide (sulfated) is 300-fold more active than the non-sulfated CCK octapeptide (Cay24404). Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.1,2 It is a cleaved product of the full CCK preprohormone that is more potent than the full-length enzyme in stimulating contraction of guinea pig gallbladder but with a shorter duration. CCK octapeptide (sulfated) is 300-fold more active than the non-sulfated CCK octapeptide (Cay24404). Cholecystokinin (CCK) protein function: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. [The UniProt Consortium]