Candesartan Cilexetil
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26... more
Product information "Candesartan Cilexetil"
Description: Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). Upon hydrolysis to candesartan during gastrointestinal absorption, it selectively competes with angiotensin II for binding to the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation. Target: RAAS, Apoptosis. Smiles: C(N1C=2C(N=C1OCC)=CC=CC2C(OC(OC(OC3CCCCC3)=O)C)=O)C4=CC=C(C=C4)C5=C(C=CC=C5)C=6NN=NN6. References: See S, et al. Am J Health Syst Pharm,2000,7(8), 739-746.
| Keywords: | TCV-116 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2400 |
Properties
| MW: | 610.66 D |
| Formula: | C33H34N6O6 |
Database Information
| CAS : | 145040-37-5| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H361 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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