Calmidazolium chloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist with a Kd of 3... more
Product information "Calmidazolium chloride"
Description: Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist with a Kd of 3 nM, which inhibits CaM-dependent phosphodiesterase (IC50 = 0.15 µM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase (IC50 = 0.35 µM). It also induces apoptosis in certain cancer cell lines. Target: Autophagy, CaMK. Smiles: [Cl-].Clc1ccc(cc1)C(c1ccc(Cl)cc1)[n+]1ccn(CC(OCc2ccc(Cl)cc2Cl)c2ccc(Cl)cc2Cl)c1. References: Gietzen K, et al. Comparison of the calmodulin antagonists compound 48/80 and calmidazolium. Biochem J. 1983 Dec 15,216(3):611-6.
| Keywords: | R 24571 |
| Supplier: | TargetMol |
| Supplier-Nr: | T10667 |
Properties
| MW: | 687.7 D |
| Formula: | C31H23Cl7N2O |
Database Information
| CAS : | 57265-65-3| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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