Caffeic Acid Phenethyl Ester
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation... more
Product information "Caffeic Acid Phenethyl Ester"
Description: Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1). Target: NF-kappaB, Apoptosis. Smiles: Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O. References: Natarajan K, et al. Proc Natl Acad Sci U S A. 1996, 93(17), 9090-9095.
| Keywords: | CAPE, Phenylethyl Caffeate |
| Supplier: | TargetMol |
| Supplier-Nr: | T6429 |
Properties
| Application: | Inhibits NFkappaB activation |
| MW: | 284.31 D |
| Formula: | C17H16O4 |
Database Information
| CAS : | 104594-70-9| Matching products |
| KEGG ID : | K04735 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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