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Description: Caerulomycin A (Caerulomycin) (Cerulomycin, Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-beta-Smad3 protein signaling via suppressing interferon-gamma-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases. Target: Antifungal. Smiles: COc1cc(\C=N\O)nc(c1)-c1ccccn1. References: Gurram RK, et al. Caerulomycin A enhances transforming growth factor-beta (TGF-beta)-Smad3 protein signaling by suppressing interferon-gamma (IFN-gamma)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20,289(25):17515-28.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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