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Description: C-82 is a specific CBP/beta-catenin antagonist. It inhibits the binding between beta-catenin and CBP and increases the binding between beta-catenin and p300. Target: Epigenetic Reader Domain, Wnt/beta-catenin. Smiles: [H][C@]12[C@H](C)N(Cc3cccc4cccnc34)C(=O)[C@H](Cc3ccc(O)cc3)N1C(=O)CN(C)N2C(=O)NCc1ccccc1. References: Osawa Y, et al. Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/beta-Catenin Reduces Liver Fibrosis in Mice. EBioMedicine. 2015 Oct 8,2(11):1751-8.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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