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Bucladesine is a cell-permeable, cyclic nucleotide derivative that mimics the action of endogenous cyclic adenosine monophosphate (cAMP) and is a phosphodiesterase inhibitor. Because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions, bucladesine is widely used in a variety of research applications.Formal Name: N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate) 2'-butanoate-adenosine, monosodium salt. CAS Number: 16980-89-5. Synonyms: DC 2797. Molecular Formula: C18H23N5O8P . Na. Formula Weight: 491.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/mL, DMSO: 5 mg/mL, PBS (pH 7.2): 10 mg/mL. lambdamax: 211, 271 nm. SMILES: O=P1([O-])OC[C@H]2O[C@@H](N3C4=NC=NC(NC(CCC)=O)=C4N=C3)[C@H](OC(CCC)=O)[C@@H]2O1.[Na+]. InChi Code: InChI=1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14,/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24),/q,+1/p-1/t10-,14-,15-,18-,/m1./s1. InChi Key: KRBZRVBLIUDQNG-JBVYASIDSA-M.
Keywords:
DC 2797, N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate) 2'-butanoate-adenosine, monosodium salt
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