BSJ-04-132

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
Cay41248-1	1 mg		-	-	5 - 10 business days*		178.00€
Cay41248-5	5 mg		-	-	5 - 10 business days*		529.00€

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A PROTAC that drives Cdk4 degradation, selectively induces the degradation of Cdk4 over Cdk6,... more

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Product information "BSJ-04-132"

A PROTAC that drives Cdk4 degradation, selectively induces the degradation of Cdk4 over Cdk6, IKZF1, and IKZF3 in a cereblon-dependent manner in Jurkat cells at 1 µM. Formulation: A solid. InChI: InChI=1S/C42H49N11O7/c1-49(2)40(58)31-22-26-23-45-42(48-37(26)52(31)27-8-3-4-9-27)46-33-14-12-28(24-44-33)51-20-18-50(19-21-51)17-6-5-16-43-35(55)25-60-32-11-7-10-29-36(32)41(59)53(39(29)57)30-13-15-34(54)47-38(30)56/h7,10-12,14,22-24,27,30H,3-6,8-9,13,15-21,25H2,1-2H3,(H,43,55)(H,47,54,56)(H,44,45,46,48). InChIKey: GWLSXEHHNOBFOI-UHFFFAOYSA-N. SMILES: O=C(NCCCCN1CCN(CC1)C2=CN=C(NC3=NC4=C(C=C(N4C5CCCC5)C(N(C)C)=O)C=N3)C=C2)COC6=CC=CC7=C6C(N(C7=O)C8CCC(NC8=O)=O)=O

Keywords:	7-cyclopentyl-2-[[5-[4-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-1-piperazinyl]-2-pyridinyl]amino]-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Supplier:	Cayman Chemical
Supplier-Nr:	41248

Properties

Application:	Cdk4 degradation driving PROTAC
Immunogen:	819.9
MW:	819.9 D
Formula:	C42H49N11O7
Purity:	>98%
Format:	Solid

Database Information

CAS :	2349356392\| Matching products
KEGG ID :	K02089 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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