Bromosulfalein

Bromosulfalein has been commonly used as both a substrate and inhibitor of organic anionic transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP1A2, and OATP2B1, as well as multidrug resistance protein 2 (MDR2). It has also been used for in vivo studies of liver and biliary system function and as an anionic dye for the quantitative estimation of protein levels in tissue homogenates or purified samples.Formal Name: 3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxy-benzenesulfonic acid, disodium salt. CAS Number: 71-67-0. Synonyms: Bromosulfophthalein, Bromosulphalein, Sulfobromophthalein, Sulphobromophthalein. Molecular Formula: C20H8Br4O10S2 . 2Na. Formula Weight: 838.0. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 5 mg/ml, Ethanol: slightly soluble, PBS (pH 7.2): 1 mg/ml. lambdamax: 230 nm. SMILES: O=C1OC(C2=CC(S([O-])(=O)=O)=C(O)C=C2)(C3=CC(S([O-])(=O)=O)=C(O)C=C3)C4=C(Br)C(Br)=C(Br)C(Br)=C41.[Na+].[Na+]. InChi Code: InChI=1S/C20H10Br4O10S2.2Na/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33,,/h1-6,25-26H,(H,28,29,30)(H,31,32,33),,/q,2*+1/p-2. InChi Key: GHAFORRTMVIXHS-UHFFFAOYSA-L.