BRD4780 (hydrochloride)
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
An imidazoline I1 receptor antagonist (Ki = 42 nM), selective for the imidazoline I1 receptor... more
Product information "BRD4780 (hydrochloride)"
An imidazoline I1 receptor antagonist (Ki = 42 nM), selective for the imidazoline I1 receptor over alpha1-, alpha2A-, alpha2B-, and alpha2C-adrenergic receptors (Kis = >100, >20, >20, and >20 µM, respectively), binds to TMED9 in a thermal shift assay and releases MUC1-fs from TMED9-containing vesicles in kidney cells isolated from patients with MUC1 kidney disease, reduces kidney MUC1-fs accumulation in transgenic mice heterozygous for human MUC1-fs at 1, 10, and 50 mg/kg
| Keywords: | AGN 192403, (1R,2R,3R,4S)-rel-3-(1-methylethyl)-bicyclo[2.2.1]heptan-2-amine, monohydrochloride |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43542 |
Properties
| Application: | Nischarin (imidazoline receptor 1) antagonist |
| MW: | 189.73 D |
| Formula: | C10H19N . HCl |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 1021868-90-5| Matching products |
| KEGG ID : | K24095 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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