BODIPY FL VH032

BODIPY FL VH032
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T41171-5mg 5 mg

7 - 10 business days*

456.00€
 
Description: BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with... more
Product information "BODIPY FL VH032"
Description: BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of VHL ligands. BODIPY FL VH032 consists of a derivative of von Hippel-Lindau (VHL) ligand VH 032 and a fluorophore BODIPY FL(with excitation peak at 504 nm and emission peak at 520 nm), joined by a polyethylene glycol (PEG) 4 linker. The BODIPY FL VH032 VHL TR-FRET signal is stable through the 90 - 300 min incubation time, and theTR-FRET binding assay is sensitive, selective and resistant to assay interference. BODIPY FL VH032 also exhibits high VHL affinity in a fluorescence polarization (FP) assay. Excitation maximum ~ 504 nm, emission maximum ~ 520 nm. References: Lin et al (2020) Development of BODIPY FL VH032 as a high-affinity and selective von Hippel-Lindau E3 ligase. ACS Omega 6 680 PMID: 33458521
Supplier: TargetMol
Supplier-Nr: T41171

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Our products are for laboratory research use only: Not for administration to humans!
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