Boceprevir
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
White to off-white solid. Soluble in DMSO (15mg/ml), ethanol (20mg/ml) or DMF (20mg/ml).... more
Product information "Boceprevir"
White to off-white solid. Soluble in DMSO (15mg/ml), ethanol (20mg/ml) or DMF (20mg/ml). Chemical. CAS: 394730-60-0. Formula: C27H45N5O5. MW: 519.7. The antiviral agent boceprevir is a protease inhibitor that covalently and reversibly binds to the catalytic site (Ser139) of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A), a serine protease that is essential for viral replication (Ki = 14nM) by cleaving the virally encoded polyprotein into mature proteins like NS4A, NS4B, NS5A and NS5B. It inhibits the NS3/4A protease in an in vitro HCV replicon system with an EC50 value of 200 nM. Boceprevir has been identified as a potential inhibitor of SARS-CoV-2 responsible for COVID-19. It inhibits SARS-CoV-2 viral replication by targeting the viral main protease Mpro (IC50 = 4.13µM).
| Keywords: | Victrelis, EBP 520, SCH 503034 |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CR1-3735 |
Properties
| Application: | Antiviral |
| MW: | 519,7 D |
| Formula: | C27H45N5O5 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 394730-60-0| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302, H361 |
| P Phrases: | P301+P312, P308+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed