Bilirubin

Bilirubin is a yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase. This reaction produces carbon monoxide and biliverdin, which is rapidly reduced to bilirubin by biliverdin reductase. Bilirubin has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions. Free and albumin-bound bilirubin can also scavenge nitric oxide (NO) and NO-related species. Unconjugated bilirubin is highly water-insoluble and must be conjugated with glucuronides to become water soluble and subsequently excreted by the liver and kidney.Formal Name: 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid. CAS Number: 635-65-4. Synonyms: Hematoidin, NSC 26685. Molecular Formula: C33H36N4O6. Formula Weight: 584.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 5 mg/ml, DMF: 0.1 mg/ml, DMSO: 0.2 mg/ml. lambdamax: 241, 451 nm. SMILES: CC1=C(/C=C2NC(C(C=C)=C\2C)=O)NC(CC3=C(CCC(O)=O)C(C)=C(/C=C4NC(C(C)=C\4C=C)=O)N3)=C1CCC(O)=O. InChi Code: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-. InChi Key: BPYKTIZUTYGOLE-IFADSCNNSA-N.