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Description: BIâ??3231 is a selective and potent inhibitor of hydroxysteroid 17ÃY-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis. Target: Dehydrogenase. Smiles: O=C1C(=CN(C(=O)N1CC)CC2=NN=C(S2)C=3C=CC(F)=C(O)C3F)C. References: Thamm S, et al. Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science. J Med Chem. 2023 Feb 2.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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