Berbamine

Description: Berbamine is a natural product extracted from Phellodendron amurense. It acts as a calcium channel blocker and possesses anti-tumor, immunomodulatory, and cardiovascular effects. Target: CaMK, Autophagy, NF-kappaB. Smiles: [H][C@]12Cc3ccc(Oc4cc(C[C@@]5([H])N(C)CCc6cc(OC)c(OC)c(Oc7cc1c(CCN2C)cc7OC)c56)ccc4O)cc3. References: Jin X , Wu Y . Berbamine Enhances the Antineoplastic Activity of Gemcitabine in Pancreatic Cancer Cells by Activating Transforming Growth Factor-beta/Smad Signaling[J]. The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology, 2014, 297(5).