BAY-179

BAY-179 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50s = 79, 38, 27, and 47 nM for the human, mouse, rat, and dog enzymes, respectively). See the Structural Genomics Consortium (SGC) website for more information.Formal Name: 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-3H-imidazo[4,5-b]pyridine. CAS Number: 2764880-87-5. Molecular Formula: C23H21N5OS. Formula Weight: 415.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: Slightly soluble, DMSO: Slightly soluble. lambdamax: 286, 310 nm. SMILES: C12=NC=CC=C1NC(CN3CCC(C4=NC(C5=CC6=C(C=CC=C6)O5)=CS4)CC3)=N2. InChi Code: InChI=1S/C23H21N5OS/c1-2-6-19-16(4-1)12-20(29-19)18-14-30-23(26-18)15-7-10-28(11-8-15)13-21-25-17-5-3-9-24-22(17)27-21/h1-6,9,12,14-15H,7-8,10-11,13H2,(H,24,25,27). InChi Key: JOCPQSJABURDDD-UHFFFAOYSA-N.