b-AP15 (NSC-687852)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-27701-1	5 mg		-	-	3 - 15 business days*		410.00€
BPS-27701-2	25 mg		-	-	3 - 15 business days*		859.00€

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Blocks 26S proteasome activity by inhibiting the ubiquitin C-terminal hydrolase 5 (UCHL5) and... more

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Product information "b-AP15 (NSC-687852)"

Blocks 26S proteasome activity by inhibiting the ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) activities of the 19S regulatory subunit without affecting the catalytic activity of the 20S core subunit. b-AP15 displays several differences to bortezomib including insensitivity to over-expression of the anti-apoptotic mediator Bcl-2 and anti-tumor activity in four solid tumor models.

Keywords:	b-AP15, NSC-687852, 3,5-Bis[(4-nitrophenyl)methylene]-1?-(1-oxo-2-propene-1-yl)-4-piperidone,
Supplier:	BPS Bioscience
Supplier-Nr:	27701

Properties

Application:	UCH-L5 or USP14 inhibitor
MW:	419.4 D
Formula:	C22H17N3O6
Format:	Posttranslational Mod.

Database Information

KEGG ID :

K05610 | Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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