Azumolene (sodium salt)

Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. It inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 µM azumolene causing a 70% reduction in SOCE in myotubes. Azumolene has utility in countering muscle dysfunction associated with malignant hyperthermia.Formal Name: 1-[[[5-(4-bromophenyl)-2-oxazolyl]methylene]amino]-2,4-imidazolidinedione, monosodium salt. CAS Number: 105336-14-9. Synonyms: EU4093. Molecular Formula: C13H8BrN4O3 . Na. Formula Weight: 371.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 2 mg/ml. lambdamax: 259, 338 nm. SMILES: BrC1=CC=C(C2=CN=C(/C=N/N3C([N-]C(C3)=O)=O)O2)C=C1.[Na+]. InChi Code: InChI=1S/C13H9BrN4O3.Na/c14-9-3-1-8(2-4-9)10-5-15-12(21-10)6-16-18-7-11(19)17-13(18)20,/h1-6H,7H2,(H,17,19,20),/q,+1/p-1/b16-6+,. InChi Key: PHJRJPWBPXLNAJ-FPUQOWELSA-M.