Avagacestat

Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-T6249-1mg	1 mg				7 - 10 business days*	33.00€
TGM-T6249-5mg	5 mg				7 - 10 business days*	70.00€
TGM-T6249-1mL	1 ml				7 - 10 business days*	80.00€
TGM-T6249-10mg	10 mg				7 - 10 business days*	118.00€
TGM-T6249-25mg	25 mg				7 - 10 business days*	224.00€
TGM-T6249-50mg	50 mg				7 - 10 business days*	325.00€
TGM-T6249-100mg	100 mg				7 - 10 business days*	473.00€
TGM-T6249-200mg	200 mg	-	-	-	7 - 10 business days*	635.00€

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Description: Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable... more

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Product information "Avagacestat"

Description: Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable gamma-secretase inhibitor of Abeta40 and Abeta42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2. Target: Gamma-secretase. Smiles: NC(=O)[C@@H](CCC(F)(F)F)N(Cc1ccc(cc1F)-c1ncon1)S(=O)(=O)c1ccc(Cl)cc1. References: Gillman KW, et al. Med Chem Lett, 2010, 1 (3), 120â?"124.

Keywords:	BMS-708163
Supplier:	TargetMol
Supplier-Nr:	T6249

Properties

Application:	Dementia therapeutic agent, gamma-Secretase inhibitor
MW:	520.89 D
Formula:	C20H17ClF4N4O4S

Database Information

CAS :

1146699-66-2| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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